At LallianSe, to ensure that New Year’s wishes don’t remain meaningless or static, we propose embedding them in a dynamic trajectory, a momentum, a vision. So yes, wishing each other a happy new year (collectively) is important to us—but not just any old way
Last year, we wanted to innovate and reinvent the way we share our greetings, imagining a format that reflects who we are. Because at the heart of LallianSe’s DNA lies the collective spirit, the desire to do things differently, and the deep conviction that it is by building together that we can go further.
This is how our collective 2025 manifesto was born: a kind of “wishing box” open to all those who envision the future of healthcare differently. Many of you participated, and it was with great joy that we highlighted your wishes throughout 2025.
So for 2026 – and beyond – share a wish in our wish box and become a contributor to the collective 2026 manifesto, which will be enriched and published later this year, where each author will be featured.
3rd edition : January 26th 2026, at Institut Curie
The winning team of the SECOND edition is putting its title back on the line!
Join us for a unique theatrical improvisation match, where the promotion of research takes on a new dimension!
Same format: 3 teams of 3 candidates, formed in advance. Each team, composed of an Entrepreneur / Researcher, an Investor and a representative of a technology transfer organization – where each does not play their role – will compete in comparative improvisation around a point of negotiation of a letter of intent.
Between experience, fantasies and realities, the players will stage the funny situations – or less! – of the negotiations, divergences and perspectives that form the backstage of innovation and reveal the different points of view.
The winning team will be elected by applause, and the refereeing, according to the rules of theatrical improvisation, will allow the orchestration of an animation of approximately 1h15, punctuated by dynamic exchanges with the guests. The evening will continue around a friendly cocktail.
Stay tuned to discover every week the talents of #LImprodelaValo, where innovation and improvisation meet!
2nd edition : January 27th 2025, at Institut Pasteur
The winning team of the first edition is putting its title back on the line!
Join us for a unique theatrical improvisation match, where the promotion of research takes on a new dimension!
Same format: 3 teams of 3 candidates, formed in advance. Each team, composed of an Entrepreneur / Researcher, an Investor and a representative of a technology transfer organization – where each does not play their role – will compete in comparative improvisation around a point of negotiation of a letter of intent.
Between experience, fantasies and realities, the players will stage the funny situations – or less! – of the negotiations, divergences and perspectives that form the backstage of innovation and reveal the different points of view.
The winning team will be elected by applause, and the refereeing, according to the rules of theatrical improvisation, will allow the orchestration of an animation of approximately 1h15, punctuated by dynamic exchanges with the guests. The evening will continue around a friendly cocktail.
Stay tuned to discover every week the talents of #LImprodelaValo, where innovation and improvisation meet!
[#EVENT] Institut Curie x Institut Pasteur x LallianSe
🎭 L’Impro de la Valo #2 : what a game! 🥊
THANK YOU to all those who made this evening a unique and memorable moment!
In the cage of the Institut Pasteur, between bursts of laughter, voting cards, fouls, whistles, Marseille (or Brazilian, or American) accents, sharp strategy and overflowing creativity, 12 players, 3 captains, 2 MCs, and 1 referee brought to life a battle around innovation.
Whether they played in trios, duos or even alone against each other, a huge BRAVO to our participants:
🎉 Congratulations to the big winners of this edition: Nicolas, Amandine & Guillaume aka #greenteam ! A well-deserved victory after an incredible performance on stage.
Of course, thank you to our enthusiastic audience, who played the game until the end with their votes and their communicative energy!
This week, we are pleased to introduce you to the second master of ceremonies… Player last year (#teamrouge), Miranda DELMOTTE (Hub Innovation AP-HP,) returns this year in a new role as master of ceremonies. Alongside Stephane, they will be able to electrify the atmosphere and guide the teams through the unexpected challenges of this edition.
But that’s not all…
And finally, for this last week before the big day, we are pleased to present the 3 captains: : Jérémie Weber the host of the 1st edition, Julie Rachline captain of the victorious team (#teamblue) and Alexandre Batch, PhD – MBA host of this 2nd edition.
January 9th, 2025
Before the Christmas break, we had the pleasure of introduing our 9 players , as well as Hélène Chausson (BrainTale) who will once again be in the spotlight this year with her dual role as referee and improvisation coach.
Last year as a player (#redteam), he returns this year in a brand new role: master of ceremonies!
With boundless energy, he will know how to maintain the electric atmosphere of the event… but be careful, he will not be alone… Who will be by his side?!
December 19th, 2024
This week, we are pleased to introduce you to the last of the 9 players who will take the stage :
We also have the honor of introducing Hélène Chausson(BrainTale) who will once again be in the spotlight this year with her dual role as referee and improvisation coach. With her unique expertise, Hélène will guarantee rigor, impartiality and an expert – and incorruptible – eye on the teams’ performances.
And since good news never comes alone, we have two other surprises in preparation: the two masters of ceremonies who will guide this incredible evening.
Friday, December 19th, 2025, from 12 to 1pm. Video conference on Teams, registration required.
LallianSe invites you to embark on a new expedition: webinars to explore the major stages of a healthy company’s financial trajectory.
🎯 The goal? To provide a compass to navigate these times of uncertainty, questioning, and adaptation. Each episode will draw on the experience of the ecosystem—entrepreneurs, investors, experts—to steer the right equation: the right dynamics, with the right people, at the right time.
Episode 6 – Looking for cash: where to find the first euros? Grants, loans, competitions, BPI, Business Angles: how to launch without breaking the bank?
What are the most suitable funding sources for a quick and secure launch?
How can you identify and leverage public funding mechanisms (grants, aid, loans)?
How can you avoid the pitfalls of initial fundraising rounds and maximize your chances of success?
Through concrete examples—both successful experiences and course adjustments—we will explore the levers of financing early developments without unnecessarily diluting capital or unbalancing the strategy.
The aim of this webinar: to share practical keys to move from plan to action, reduce the risks of failure linked to execution and inspire concrete strategies to move your startup forward.
Friday, December 19th, 2025, from 12 to 1pm.Video conference on Teams, registration required. LallianSe invites you to embark on a new expedition: webinars to explore the major stages of a … Continue reading “Episode #6 – #MoneyQuest webinar series”
Friday, November 28th, 2025, from 12 to 1pm.Video conference on Teams, registration required. LallianSe invites you to embark on a new expedition: webinars to explore the major stages of a … Continue reading “Episode #5 – #MoneyQuest webinar series”
Friday, October 17th, 2025, from 12 to 1pm.Video conference on Teams, registration required. LallianSe invites you to embark on a new expedition: webinars to explore the major stages of a … Continue reading “Episode #4 – #MoneyQuest webinar series”
When healthcare professionals’ ideas become concrete solutions: a comparative look at Pikidou and T-OUT & Romain Gombert (Craft & Care).
Because they are closest to patients, their practices, and their needs, healthcare professionals’ ideas and insights have immense innovative potential – provided they are encouraged, listened to, supported, and put into action.
This is the ambition behind our commitment through the #ChallengeInnovation, calls for projects initiated and managed within the APHP.Sorbonne University Hospital Group: to uncover these ideas from the field and empower them to become reality. Today, we are proud to share the story of two projects that illustrate this conviction: Pikidou, conceived and led by Cécile Combes, and T-OUT, conceived and led by Sandrine Bottius and now continued by Natasha Figueiredo.
Two unique projects, two distinct contexts, two different editions of the Challenges Innovation , but the same ambition: to meet concrete needs with simple, human, and effective solutions. Both were supported by #LallianSe, received financial backing, and were co-developed with the same partner, Romain Gombert, founder of Craft & Care.
Pikidou: A fun cactus to ease the stress of pediatric care
Winner of the Challenge Innovation #2 in 2021, Cécile Combes, a physiotherapist at the Cystic Fibrosis Resource and Competence Center of the Pediatric Pulmonology Department at Hôpital Armand-Trousseau (#APHP), is the creator of the #Pikidou project.
Pikidou was born from a simple observation:
«Recreational tools, although they exist, are often put away and therefore underutilized. I wanted to make them visible, accessible, and above all, fun for children. » Cécile Combes
From this observation, an idea was born: a mobile, colorful, and expressive cactus-shaped distraction tower. Incorporating nitrous oxide (MEOPA) for treatment, it offers playful distractions attached to its “spines,” chosen directly by the children. Transforming what is often an anxiety-inducing moment into a gentler experience, Pikidou has become much more than a device: it’s a daily companion for hospitalized children.
« Pikidou is now part of the service and evolves with the seasons. Children with chronic illnesses are delighted to see him change and come to treatment more readily. He’s a real icebreaker!» Cécile Combes
How did the idea become a reality?
Thanks to a grant of €10,000 and support from LallianSe valued at €13,500, Cécile was able to turn an initial idea into a device used daily in her department.
To bring this idea to fruition, LallianSe acted as a catalyst by connecting her with Romain Gombert.
An engineer and designer, Romain specializes in medical engineering and innovation management. After leading the #LivingLab at the Paris Brain Institute (#ICM) until 2021, he founded Craft & Care, an organization dedicated to the design and development of healthcare innovations at the intersection of design, technology, and clinical practice. Having been connected with LallianSe for several years at the Pitié-Salpêtrière site, where Romain’s activities at the ICM were located, Romain’s involvement seemed an obvious choice when Cécile expressed her need. It was an intuitive understanding of the potential for collaboration, both operational and personal, which quickly materialized.
« LallianSe was my very first partner, the one who enabled me to turn an idea into reality and lay the foundations for what is now Craft & Care », says Romain Gombert.
With him, Cécile discovered the prototyping process, the technical constraints, and the solutions adapted to a healthcare environment.
Beyond the result, this collaboration illustrates the strength of the bond between healthcare professional and expert: a pragmatic and human co-creation, where each idea takes shape through mutual understanding and a convergence of need and feasibility.
« Communication with Romain was easy and fluid. His relational and technical knowledge allowed us to move quickly. He made me different design proposals and even invited me to attend the laser cutting of the plexiglass in a Parisian workshop: it was fascinating ! », she recalls.
What is the concrete impact for patients and staff?
The impact is tangible: children take ownership of the character, become attached to it, and smile even before their treatment begins. The project has become a reality!
«Since Pikidou was introduced, children come to the first aid station more willingly, simply to see it or choose their favorite toy. The MEOPA is hidden in the cactus, which makes the experience less medical and more playful. » Cécile Combes.
The system has also changed the team dynamic: it fosters communication, camaraderie, and gives renewed meaning to the moments shared with the young patients. In an often hectic environment, Pikidou brings a touch of lightness and humanity.
And now?
The adventure doesn’t end there. Presented at the AP-HP Innovation Day and registered with the #OTTPI (AP-HP Technology Transfer & Innovation Hub), Pikidou is now attracting the interest of external stakeholders. Discussions have begun with companies to explore wider distribution, and Cécile is considering an impact study to scientifically validate its added value.
« For my part, I no longer miss any calls for projects because you only win if you play… » explains Cécile.
Son expérience est devenue une source d’inspiration pour ses pairs.
« The Challenge Innovation is a huge facilitator of turning dreams into reality. Without LallianSe, Pikidou would not exist in this form. »
What if healthcare innovation reshaped the hospital?
Beyond the technology itself, Pikidou illustrates a fundamental dynamic: that of a hospital transforming itself through its own teams. The involvement of healthcare professionals in innovation goes beyond simply implementing projects; it renews the culture, practices, and perspective on care. Encouraging innovation is also essential for the well-being of healthcare professionals, beyond just the patients themselves!
Why not consider hospital innovation as also stemming from ideas born on the ground and nurtured by the patient relationship? Can the involvement of healthcare professionals in innovation truly change the way the hospital operates?
Before that, let’s discover another winning project of the Challenge Innovation, which shares this same ambition to rethink the patient journey through the creativity and commitment of its teams: T-OUT.
T-OUT: A digital escape game to support the transition from pediatric to adult care
Winner of the Grand Prize at the Challenge Innovation #3 in 2022, T-OUT is a digital escape game conceived by Sandrine Bottius, then a care pathway coordinator in the pediatric-to-adult transition service at Pitié-Salpêtrière Hospital (AP-HP), now led by Natasha Figueiredo.
Their ambition? To support adolescents with chronic illnesses through a key stage in their care journey: the transition from pediatric to adult care. This pivotal moment, often dreaded by patients and a source of disruptions in their care pathway, inspired Sandrine:
« I saw firsthand the difficulties faced by young patients during their transition to adult care. I had this somewhat unusual idea of using games to address a very serious issue: preventing disruptions in healthcare pathways. »
Thus was born T-OUT, a digital escape game that is fun, educational and therapeutic, designed to help young people understand, anticipate and experience this transition more serenely.
How did the idea become a reality?
Winner of the Grand Prize at the Challenge Innovation #3, T-OUT received a grant of €12,000 and support from LallianSe worth approximately €16,000. Thanks to this support, the idea was transformed into a concrete and operational digital tool—and, most importantly, one used by the patients themselves.
LallianSe supported Sandrine at every stage: project structuring, selection of the technical provider, development strategy, and educational positioning.
« The 2022 Challenge Innovation was a fantastic sounding board: it allowed us to move from an idea to a recognized and supported project, with real legitimacy », explains Sandrine.
To bring this project to fruition, Romain Gombert was once again called upon. Already a partner on Pikidou, he contributed his technical expertise and understanding of hospital challenges, in addition to his project management and innovation development skills.
« Having already known the health sector, Romain was able to translate an innovative but still abstract idea into a concrete digital tool. He made it possible to optimize the technical choices, respect the budget framework without giving up on the objectives, and ensure the feasibility of the project », says Sandrine.
This collaboration, fueled by the same spirit of co-creation as for Pikidou, allowed T-OUT to find its final form: an immersive and educational escape game, co-constructed with patients, caregivers in pediatrics and adult care, around a common objective — to facilitate the transition between two worlds of care.
« Being surrounded and supported allowed me to turn obstacles into opportunities to consolidate and strengthen the project», says Sandrine.
What impact will this have on patients and staff?
Since its launch in the fall of 2024, T-OUT has been used in several hospital units. It is offered before or during the transition to adult wards to help young people become familiar with this new environment.
« Some patients told us that T-OUT helped them to better visualize what awaited them in the adult sector. This de-dramatized the transition and opened up discussion on topics they would not have spontaneously brought up», explains Natasha Figueiredo.
From the teams’ perspective, the feedback is equally positive: the game becomes a concrete tool for approaching the transition differently, in a more playful and interactive way:
« The involvement of healthcare professionals in innovation is essential to support the evolution of patients, especially younger generations born in a digital world. We need to speak the same language to create a strong bond of trust », emphasizes Natasha.
In parallel, T-OUT is the subject of a clinical study conducted at the E3M Institute, as part of a call for projects from the Fondation Maladies Rares on social and therapeutic innovations. The objective: to scientifically measure the effectiveness of the tool on quality of life and adherence to care.
And now?
Today, T-OUT continues its deployment in pediatric and adult services. It serves both as a therapeutic education tool and as a means of dialogue between patients and caregivers.
« Being able to rely on T-OUT makes us better equipped to support the transition. The tool makes this moment more concrete and more engaging for young people », observes Natasha.
For Sandrine, this adventure is also a lesson in confidence:
« An idea, even if it seems atypical or ambitious, always deserves to be explored. The important thing is to lay the first stone, share your idea, and surround yourself with the right people. »
Thanks to LallianSe – Life Sciences Integrator & Craft & Care, T-OUT has found the right balance between creativity, scientific rigor, and technical feasibility. And above all, it demonstrates that a project born from the field can become a useful, recognized, and shared tool.
From Pikidou to T-OUT: when healthcare professionals invent the hospital of tomorrow
From the Pikidou interactive tower to the T-OUT escape game, these two projects share much more than just a common support system: they embody the ability of healthcare professionals to imagine and build innovation in a concrete and effective way. Starting from needs observed firsthand, Cécile Combes, Sandrine Bottius, and Natasha Figueiredo have proven that healthcare creativity can be transformed into concrete, useful, and impactful solutions for both patients and staff.
But if their projects were able to come to fruition, it is also thanks to an essential link in this innovation chain: operational and technical implementation and prototyping. Because to move from idea to object, from concept to tool, it is still necessary to find the right partner, capable of understanding the language of healthcare while mastering that of engineering and design, and of guiding these early phases.
And this is precisely where Craft & Care and Romain Gombert come in, who alone embody the junction between innovation, clinical practice and technology.
Engineering at the service of ideas: the key contribution of Craft & Care
Pikidou and T-OUT share the commonality of having been developed with the expertise of Romain Gombert through Craft & Care, “a prototyping workshop dedicated to care.”
« My role is to provide a mini product team – product manager, designer, developers – capable of transforming an idea into a functional and testable prototype », he explains.
Translating an often abstract idea into a realistic technical solution, while respecting budgetary constraints and the hospital environment, is a major challenge. But it is also what makes these collaborations so valuable.
« The alliance between a healthcare professional, who understands the realities on the ground, and a product team, who have mastered the technologies, is the best way to provide relevant and effective solutions », says Romain.
Beyond the technical aspects, he emphasizes the human dimension of these projects:
« Seeing the smiles of caregivers and patients when they see the first results is a real reward. And it also has a ripple effect: other teams are becoming interested, which proves the usefulness of this approach. »
Thanks to this approach, Craft & Care positions itself as an essential link between the caregiver’s vision and the realization of the project. And it is precisely this connection, initiated and supported by LallianSe, that makes the transition from dream to reality possible.
Transforming the culture of innovation in hospitals
Beyond the direct benefits for patients, projects like Pikidou and T-OUT demonstrate how innovation can also transform those who champion it and the institutions that support them. For healthcare professionals, it’s an experience of renewed recognition and confidence, an improvement in well-being and quality of work life – among other things.
For healthcare facilities, it’s an opportunity to establish a new culture: that of an agile hospital, where initiative and creativity are recognized as drivers of transformation just as much as research or technology.
Cécile Combes sees it as a powerful engine of collective motivation
« Highlighting the ideas of paramedics is a fantastic tool for recognition. It changes the dynamics of teams and even the way the hospital operates. »
Sandrine Bottius confirms that this dynamic goes far beyond the scope of a single project:
« Encouraging innovation in healthcare facilities means first and foremost creating a culture open to experimentation. It is necessary to value initiatives from the field and offer structured support to transform ideas into concrete projects.»
From an engineering perspective, Romain Gombert also observes the chain effects:
« Seeing healthcare professionals regain confidence in their ability to innovate is inspiring. And when their projects come to fruition, it encourages other teams to question, create, and propose. This is how a true culture of hospital innovation is built. »
In short, each project we initiate acts as a spark of innovation, fueling a broader transformation: that of a hospital system where care and innovation mutually enrich each other, and where the field becomes the driving force of change. And that’s also part of our DNA at LallianSe – sparking innovation!
The final word: Dare to take the plunge!
If there’s one lesson to be learned from Pikidou and T-OUT’s journeys, it’s that you don’t need to have all the answers to innovate. What matters is taking the first step—with conviction, curiosity, and courage.
Our three protagonists share the same message:
« “Go for it, dare to try! You have nothing to lose and everything to gain,” encourages Cécile. “The important thing is to lay the first stone and surround yourself with the right people. Obstacles can be overcome if you stay focused on the project’s purpose,” adds Sandrine. “My advice: dare to embark on this collaborative project, because it’s in this dialogue between medical expertise and technological innovation that the most useful solutions are born », concludes Romain.
At LallianSe, we are proud to be the catalyst that connects ideas, expertise, and resources to transform healthcare professionals’ intuitions into concrete solutions for patients. These interwoven stories prove it: when healthcare professionals are given the tools to innovate, the hospital of tomorrow is being built today.
And this is just the beginning… In our next article, we will delve deeper to understand why and how healthcare professionals must be at the heart of hospital transformation.
Friday, November 28th, 2025, from 12 to 1pm. Video conference on Teams, registration required.
LallianSe invites you to embark on a new expedition: webinars to explore the major stages of a healthy company’s financial trajectory.
🎯 The goal? To provide a compass to navigate these times of uncertainty, questioning, and adaptation. Each episode will draw on the experience of the ecosystem—entrepreneurs, investors, experts—to steer the right equation: the right dynamics, with the right people, at the right time.
Episode 5 – Governance: How to Surround Yourself with the Right People – Independent Investors & Board Members – for Effective Management?
The board is in place; how can you make the most of it?
Is a balanced governance structure possible?
How can you structure and pace the board for effective management?
Through concrete examples—both successful experiences and course adjustments—we will explore the key role of governance.
The aim of this webinar: to share practical keys to move from plan to action, reduce the risks of failure linked to execution and inspire concrete strategies to move your startup forward.
Friday, December 19th, 2025, from 12 to 1pm.Video conference on Teams, registration required. LallianSe invites you to embark on a new expedition: webinars to explore the major stages of a … Continue reading “Episode #6 – #MoneyQuest webinar series”
Friday, November 28th, 2025, from 12 to 1pm.Video conference on Teams, registration required. LallianSe invites you to embark on a new expedition: webinars to explore the major stages of a … Continue reading “Episode #5 – #MoneyQuest webinar series”
Friday, October 17th, 2025, from 12 to 1pm.Video conference on Teams, registration required. LallianSe invites you to embark on a new expedition: webinars to explore the major stages of a … Continue reading “Episode #4 – #MoneyQuest webinar series”
A look back at two months driven by reflection and action — fully aligned with our DNA: building bridges, inspiring, and supporting health innovators. Here’s a recap of the highlights from the past few weeks.
#IMPULSE
It’s back-to-school season! And at #LallianSe, we’re starting strong… by playing with space and time to foster connections and spark action.
After a successful first edition, our second #CEOonly session gathered a circle of leaders around Jean-Charles Trouabal for a confidential moment of sharing. Authenticity, trust, and openness once again made this space a unique time dedicated to strategic reflection and mutual listening.
At the start of summer, LallianSe invited you to embark on a new expedition: a series of webinars exploring the key milestones in the journey of innovative health companies.
After exploring funding and structuring dynamics, we continued our series with two new episodes:
Episode #3 – Fractional Executives, with Fabienne Hermitte, dedicated to the added value of medical affairs and fractional leadership for innovative companies. How can you access the right expertise at the right time while remaining flexible? That’s the approach #LallianSe has been pioneering for over a decade: #FractionalExecutives. But beware — not everyone can improvise as a fractional leader!
During our participation at MedTech World in Malta last year, it became clear that we shared more than a vision — we shared values. This year, our commitment to MedTech takes shape through a strengthened partnership.
On the agenda: a debate between investors and entrepreneurs to highlight the attractiveness of our ecosystem, with a French delegation traveling to Malta for the event. Meet our panelists:
A year ago, in autumn 2024, during the Brain Innovation Days, Braintale — represented by its CEO Julie Rachline — won the pitch competition, driven by a strong ambition: transforming #BrainCare.
On October 16th, 2025, one year later, Julie— former CEO of Braintale and now President of LallianSe — returned to the Brain Innovation Days stage, this time invited to share her experience following the liquidation of Braintale, her learnings, and her challenges alongside:
For several years, this partnership has fostered knowledge sharing and the emergence of innovative projects during these major annual gatherings. Thanks to our partnership, you can enjoy a 20% discount on full passes (applied to the “late registration” rate) — register now using the code : Lallianse_0306. See you in Strasbourg on December 2nd & 3rd, 2025!
Our #manifeste collectif continues to take shape, nourished by your contributions. In recent weeks, Julie Rachline, Alexandre Templier, Emmanuelle Voisin, Alain Chatelin, and Miranda Delmotte have shared their hopes and convictions for a more human, more ambitious, and more collective innovation in health..
Supporting innovation in health effectively means understanding the realities on the ground.
In 2017, we took a bold step: creating the first startup hosting space within a hospital, at Pitié-Salpêtrière (AP-HP). After seven years, this immersion has shaped a unique experience that we now want to share through a dedicated article series. Why this series?
Because innovation, to be meaningful, must be designed with healthcare professionals. Because these years of #immersion have shown us that ideas born in the field, when supported, become concrete solutions serving everyone.
In the 1st article we revisit the genesis of this ambitious idea:
How did this immersion open unprecedented dialogue between caregivers, hospital management, and innovators? Why and how did we launch the #ChallengeInnovation contests? And what lessons have we learned after 4 editions and 7 award-winning projects?
In the 2nd article we continued this storytelling with a concrete and inspiring example: OB-E, a project born from the expertise and commitment of caregivers to address a major public health challenge — obesity.
The end of 2025 promises to be just as dynamic: new encounters, new synergies, and always the same ambition — to reveal, structure, and accelerate health innovation and those who drive it forward.
A look back at a spring and early summer rich in encounters, sharing, and new impetus. These last three months have once again reinforced our mission: to connect, inspire, and … Continue reading “About last months May, June & July 2025”
Two months of strategic reflection, experience sharing, and renewed energy – March and April reinforced our ambition: to support healthcare innovators as closely as possible to their realities. A look … Continue reading “About last months : March & April 2025”
7 years of hospital immersion: Spotlighting OB-E, an ambitious initiative led by caregivers for the benefit of patients.
In the first article in this series, we presented LallianSe’s choice to immerse itself in the heart of the hospital, at Pitié-Salpêtrière Hospital, and the genesis of the Innovation Challenge. These calls for projects were designed as springboards to support and promote innovation born in the hospital field, driven by those who care for patients every day
Today, this second article highlights the OB-E project, which particularly caught the jury’s attention during Innovation Challenge #4.
OB-E: An Essential Innovative Response to Address a Major Public Health Issue
Led byEve DESNOYERS, then a dietitian and coordinator of the Obesity Specialized Center (CSO) in the Ile-de-France region (IDF), and Professor Judith Aron-wisnewsky, a physician-researcher specializing in obesity and related diseases, OB-E offers personalized e-learning support to patients living with overweight or obesity, complementing medical monitoring. Since then, the team has been expanded with the participation of Camille Salaün (new coordinator of the CSO in the IDF Est region and dietitian) and DrMargot Denismedical coordinator of the CSO in the IDF Est region) for the production of new ETP modules.
In France, nearly 48.3% of the population is overweight or obese, a figure that is constantly increasing. Obesity also affects the most socioeconomically disadvantaged twice as frequently. The provision of care, and in particular Therapeutic Patient Education (TPE), remains limited: often offered only in person, it effectively excludes many patients who do not have access to care. This observation led to the creation of OB-E, which makes therapeutic and preventive tools recommended by the French National Authority for Health(HAS), accessible (free of charge for patients), but which are often difficult for patients to access.
From the Innovation Challenge to the creation of a foundation!
When Judith Aron-Wisnewsky and Eve Desnoyers decided to apply for the Innovation Challenge, it was with conviction and ambition:
« We strongly believed in the potential of our project and wanted to share it with others to continue to grow it.»
Winner of the second prize in the Innovation Challenge #4, OB-E received a financial grant of €7,000 and skills sponsorship from LallianSe for 6 months. At the end of this skills sponsorship phase, LallianSe continued its pro bono support – a strong and obvious commitment on the part of the team given the challenge of the project, its potential impact, and the quality of the relationship established with the project leaders. Very quickly, the project became an entrepreneurial adventure for which it was necessary to define the trajectory. Judith Aron-Wisnewsky and Eve Desnoyers explain:
« LallianSe was our guide through the fog, always guiding us back on the path to move forward. Thanks to their advice, we were able to transform a project into an adventure: the creation of a sheltered foundation under the aegis of the Fondation pour la Recherche Médicale (FRM). LallianSe shared their network of contacts with us to connect us with the FRM. We would never have known who to approach, or dared to approach the FRM, or even thought about becoming a sheltered foundation. We would never have imagined how to approach funders (through sponsorship).»
This pivotal step came to fruition thanks to a connection initiated by LallianSe, which has been working with the Fondation pour la Recherche Médicale (FRM) for several years. This commitment was accompanied by a strong moral and ethical ambition, without which the collaboration with the FRM would not have been possible. It is precisely this dimension that has made it possible to build a solid, sustainable foundation project aligned with the public interest. Valerie Lemarchandel, Scientific Director of the FRM and member of the Executive Board, recalls:
«What particularly convinced us was the scientific relevance of the project, the potential impact on patients, the scope of general interest, as well as the remarkable commitment and energy of the two project leaders.»
The FRM then proposed a solid legal, administrative and scientific framework, allowing the OB-E project to gain legitimacy and greater sustainability, Valérie Lemarchandel explains:
« The mention under the aegis of the Foundation for Medical Research strengthens the visibility and credibility of the initiatives supported.»
A tripartite collaboration based on trust
This synergy between the two project leaders, the FRM and LallianSe, was decisive and was able to be built on solid foundations:
« From the outset, the collaboration ran smoothly, with a clear division of roles, a dialogue marked by great listening skills and a real dynamic of co-construction » emphasizes Valérie Lemarchandel.
For Judith Aron-Wisnewsky and Eve Desnoyers, the challenge was to navigate a path strewn with administrative and regulatory pitfalls, but always relying on valuable advice and shared expertise.
And today?
The OB-E Foundation, under the aegis of the Fondation pour la Recherche Médicale, was born. OB-E is now deployed at the Pitié-Salpêtrière Hospital, where it has been widely adopted by healthcare teams and used by more than 300 patients, enabling the initiation of real-life research projects targeted by the ambition of the sheltered foundation (in order to evaluate the benefits of this care tool in real life). Initial additional funding has already been obtained, the team mobilized around the project has grown, with the contributions of Margot Denis and Camille Salaün opening up new perspectives:
« Our objectives are to implement the solution to new themes and to measure the impact of e-course support, while ensuring the sustainability of the structure.»
The role of caregivers in hospital innovation
This adventure illustrates two strong convictions that we have seen over the course of the various editions of the Challenge Innovation:
A project can only succeed if it is driven by a complementary team that translates patient needs into reality. Paramedics and physicians are thus the two pillars of this essential alliance to bring innovation to life—beyond individual energy and willpower.
While ideas are the foundation, their appropriate articulation and perspective are crucial. Operational and strategic capabilities, with a 360° vision, are required to bring projects to fruition.
Judith Aron-Wisnewsky and Eve Desnoyers testify: « Caregivers are constantly innovating to adapt to the needs of their patients. But to innovate beyond daily practice, you have to dare, and LallianSe was the catalyst.»
Beyond these observations, the OB-E project also highlights the exceptional motivation and energy of caregivers: capable of carrying out a demanding and above all engaging initiative, alongside their daily mission with patients.
The final word
For both the FRM and LallianSe, OB-E is an ideal example of what collaboration between fieldwork, strategic support and scientific expertise can produce.
« LallianSe plays a central role in identifying and supporting innovative projects with a strong impact on health. A true catalyst, it facilitates strategic connections and optimizes the chances of success » concludes Valérie Lemarchandel.
At LallianSe, we are proud of this support, and convinced that innovation is born above all from the meeting of skills, ambition and trust.
In our next article, we will continue this series with two other winning projects: T-OUT and Pikidou, supported by the experience of Romain Gombert, who helped to bring these projects to fruition.
When healthcare professionals’ ideas become concrete solutions: a comparative look at Pikidou and T-OUT & Romain Gombert (Craft & Care). Because they are closest to patients, their practices, and their … Continue reading “Hospital Immersion Series – Article #2bis”
7 years of hospital immersion: Spotlighting OB-E, an ambitious initiative led by caregivers for the benefit of patients. In the first article in this series, we presented LallianSe’s choice to … Continue reading “Hospital Immersion Series – Article #2”
Innovation by and for caregivers: from idea to reality Or how the daily lives of caregivers can also be translated into innovations and benefits for everyone, including the hospital Context … Continue reading “Hospital Immersion Series – Article #1”
At LallianSe, we believe that healthcare innovation can only emerge through cross-stakeholder collaboration: researchers, entrepreneurs, industry players, patient associations, institutions, and investors.
Our approach is to build bridges, leverage shared experiences, and define the most adapted journey — whether it follows an industrial strategy, a startup mindset, a foundation model, or other opportunities.
A renewed commitment
Julie’s participation at Brain Innovation Days 2025 is not just symbolic. It reflects our ongoing commitment to contribute differently to the future of BrainCare and to pursue this exciting collective journey.
We are proud to renew our engagement towards a better future in neuroscience and brain health.
From pitch winner… to stage speaker! Last year, at Brain Innovation Days 2024, Braintale won the pitch competition driven by a bold ambition: transforming #BrainCare. One year later, on October … Continue reading “Brain Innovation Days 2025”
[#PARTNERSHIP] Innovation doesn’t happen alone. It requires (great) ideas, (bold) strategy, (smart) execution… — and the (amazingly) right people. When we attended MedTech World in Malta last year, it became … Continue reading “Medtech Malta 2025”
[#PARTNERSHIP] Innovation doesn’t happen alone. It requires (great) ideas, (bold) strategy, (smart) execution… — and the (amazingly) right people.
When we attended MedTech World in Malta last year, it became obvious we shared more than a vision – we shared values. Today, we are proud to announce our partnership to support a bold and international ambition for the Medtech environment.
At upcoming #MedTechMalta2025, #LallianSe together with MD101 will shed the light on the French Medtech ecosystem – join us and stay tuned !
Three partners. Three perspectives. One mission : support medtech leaders to turn breakthrough ideas into successful global market-ready solutions.
At LallianSe, we don’t just connect. We build. We translate. We amplify.
💥 See you in Valletta, November 2025
[#PARTNERSHIP] After distorting time… let’s make way for space!
In the geographical sense, of course. And since it’s unthinkable to develop ambitious projects without thinking globally and internationally, we at LallianSe – Life Sciences Integrator are offering the chance to confront international#MedTechs.
That’s why we’re very pleased to announce this partnership with MedTech World for the upcoming #MedTechMalta2025, from November 12th to 14th.
On the agenda: a debate between investors and entrepreneurs to highlight the attractiveness of our ecosystem (more info soon!) and to invite #MedTechs to be part of a French delegation. Want to join?!
For over 20 years, Catherine has supported healthcare and technology entrepreneurs, with a constant commitment to growing high-impact projects and giving them international recognition. She embodies both institutional credibility and a strong, loyal human relationship with entrepreneurs, two essential assets for making medtech companies visible and competitive.
📅 Join us on November 13th in Malta for our panel “Vive la MedTech: France as a Gateway to Global MedTech” to talk with her and discover how French investment is fueling the future of medtech.
With her extensive experience in healthcare investments, Sophie will share her perspective on driving healthcare transformation and empowering the next generation of MedTech leaders – by supporting innovative MedTech companies such as CILIATECH – Glaucoma Innovators, Damae Medical or Stilla Technologies, as well as digital health pioneers like Synapse Medicine or Implicity.
📅 Join us on November 13th in Malta for our panel “Vive la MedTech: France as a Gateway to Global MedTech” to connect capital with purpose for sustainable healthcare impact!
With her strong commitment to supporting visionary entrepreneurs, Celia has over 20 years of successful experience in hashtag#VentureCapital with a strong focus on life sciences and deeptech. At Supernova Invest, she leads investments in innovative healthcare and MedTech companies, supporting their growth from early stage to international scale.
📅 Join us on November 13th in Malta for our panel “Vive la MedTech: France as a Gateway to Global MedTech” to back bold entrepreneurs shaping the healthcare of tomorrow!
Laurent began his career in the public #French environment and the pharma industry before starting #healthcare investments 20 years ago. Now overearching the #Innobio team at Bpifrance, he contributes to shaping the future of innovation and sits on the boards of several cutting-edge companies.
📅 Join us on November 13th in Malta for our panel “Vive la MedTech: France as a Gateway to Global MedTech” to underline the attractiveness of the French innovation ecosystem !
Laure, alongside Michel Lefranc & Florian Coiseur, is the driving force behind #SurgitecRobotics, a MedTech pioneering a game-changing surgical robotics platform for hard-tissue procedures. With over 20 years of experience in finance, strategy, and entrepreneurship, she now leads the company’s vision, culture, partnerships, and equity strategy — scaling accessible, cost-efficient, premium robotic-assisted surgery to health systems worldwide.
📅 Join us on November 13th in Malta for our panel “Vive la MedTech: France as a Gateway to Global MedTech” to show how French MedTech fosters groundbreaking surgical innovation !
As CEO and Co-Founder of SurgeCare, Julien is pioneering the convergence of AI and multi-omics to revolutionize biomarker discovery and diagnostics. The company develops PreCyte, a breakthrough immune-based prognostic solution for prognosis of surgical infections, built on a unique proprietary AI platform that unifies complex omics data, aiming at transforming patient care.
📅 Join us on November 13th in Malta for our panel “Vive la MedTech: France as a Gateway to Global MedTech” to make precision medicine from the immune system a reality for patients !
Neuroscientist by training, former investor and CEO of #BrainTale & #LallianSe CEO since 2015, Julie is passionate about building bridges between science, entrepreneurship and investment. With her unique 360° perspective across the #MedTech ecosystem, she drives forward innovation by creating fertile environments where bold ideas and smart capital meet.
Recognized last year at #MedTechMalta2024 with the Female Entrepreneur Award, Julie continues to channel her energy into fostering collaboration and innovation across the MedTech community. This year, her focus is on highlighting what truly matters for MedTech entrepreneurs: strong domestic support combined with bold, global ambition — powered by the adequate investors.
📅 Join us on November 13th in Malta for our panel “Vive la MedTech: France as a Gateway to Global MedTech” to contribute to an ambitious, global and agile environment combining smart money and bold MedTechs.
